A vaccine from Moderna the US drugmaker produces a robust immunity in 45 patients used for in its early stage human trial, according to newly released data published in the peer-reviewed New England Journal of Medicine. Also, CNBC reported that about 45 patients produced neutralizing antibodies, which scientists believe is important for building immunity. It also provided more promising data that the vaccine may give some protection against the coronavirus. In the trial, each participant received a 25, 100, or 250 microgram dose, with 15 people in each dose group. Participants received two doses of the potential vaccine.
According to Moderna:
“After two vaccinations, the COVID-19 vaccine generated a “robust” immune response in all participants in all dose cohorts,”
This company also disclosed that the levels of neutralizing antibodies in patients in the high dose group were fourfold higher than in recovered COVID-19 patients.“Moderna’s chief medical officer, Tal Zaks said:
“We look forward to beginning our Phase 3 study of mRNA-1273 this month to demonstrate our vaccine’s ability to significantly reduce the risk of COVID-19 disease.”
It should be recalled that last month, the company released preliminary information from its early stage trial, but it lacked all of the data and it hadn’t been peer-reviewed yet. The newly released data provides more promising information that the vaccine may give some protection against the virus. Moderna also disclosed that the COVID-19 vaccine was generally well-tolerated, though more than half of the participants reported mild or moderate symptoms such as fatigue, muscle aches, or pain at the injection site.
Furthermore, Moderna announced it would begin its late-stage trial for its vaccine on July 27. The trial will enroll 30,000 participants across 87 locations, according to ClinicalTrials.gov.
Moderna is one of several working medical drugmakers whose discoveries are producing a potential vaccine for COVID-19. According to the World Health Organization (WHO), more than 100 vaccines are under development globally.
Hopefully the vaccine is achieved; it is going to be the most remarkable discovery ever!
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